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RIP3 (phospho Ser232) antibody

Orthogonal
Anti-RIP3 (phospho Ser232) antibody used in Western Blot (WB). GTX03683

Cat. No. GTX03683

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB

Reactivity

 Human
Package
100 μl ($399)
See all RIP3 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500-1:2000
Not tested in other applications.

Observed MW

53 kDa.

PROPERTIES

Form

Liquid

Buffer

PBS, 50% Glycerol

Preservative

0.02% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Mouse

Immunogen

A phospho specific peptide corresponding to residues surrounding S232 of Mouse Ripk3.

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

receptor-interacting serine-threonine kinase 3 , 2610528K09Rik , AW107945 , Rip3

Cellular Localization

Cytoplasm, cytosol , Cell membrane , Mitochondrion

Background

Enables NF-kappaB-inducing kinase activity and protein serine/threonine kinase activity. Involved in several processes, including execution phase of necroptosis; hematopoietic or lymphoid organ development; and regulation of programmed cell death. Acts upstream of or within several processes, including I-kappaB kinase/NF-kappaB signaling; positive regulation of intrinsic apoptotic signaling pathway; and positive regulation of protein deacetylation. Located in cytoplasm and nucleus. Is expressed in several structures, including alimentary system; hemolymphoid system gland; male reproductive gland or organ; primitive streak; and turbinate bone primordium. Orthologous to human RIPK3 (receptor interacting serine/threonine kinase 3). [provided by Alliance of Genome Resources, Apr 2022]

Database

Research Area

DATA IMAGES

Anti-RIP3 (phospho Ser232) antibody used in Western Blot (WB). GTX03683

GTX03683 WB Image

Orthogonal

WB analysis of 293T cell lysates treated by CIP at 37oC for 1 hour using GTX03683 RIP3 (phospho Ser232) antibody.
Dilution : 1:500
Loading : 25 μg per lane

REFERENCE

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REVIEW

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Package List Price ($)
$ 399